Level 12 DiseaseCackle Fever

The symptoms of cackle fever include high fever, disorientation, and frequent bouts of hideous laughter.

Stage 0: The target recovers from the disease.
Stage 1: Initial Effect: The target begins each day with no action points. Each time the target becomes bloodied, it laughs uncontrollably and is dazed (save ends). Both of these effects apply until the target is cured.
Stage 2: The target cannot gain or use action points.
Stage 3: Final State: The target is catatonic and unable to take any actions.
Check: At the end of each extended rest, the target makes an Endurance check if it is at stage 1 or 2.
16 or lower: The stage of the disease increases by one.
17-21: No Change
22 or higher: The stage of the disease decreases by one.

Published in Dungeon Master's Guide, page(s) 49.