Level 28 DiseaseFlesh Warp

The infected creature’s flesh warps and twists into disgusting demonic forms as it slowly and painfully transforms into a child of the Abyss.

Stage 0: The target is cured.
Stage 1: Initial Effect: The target’s body warps to take on a demonic form, as determined by the DM. The target loses a healing surge that it cannot regain until cured of the disease. In addition, the target takes a -2 penalty to attack rolls that target demons.
Stage 2: The target’s body continues to warp, losing almost all semblance of its original form. The target loses two more healing surges that it cannot regain until cured of the disease. In addition, whenever the target hits a demon with an attack, the target takes 15 psychic damage.
Stage 3: Final State: The target becomes a free willed sibriex spawn. Special: This final state occurs if the target progresses to it normally, or if the target dies while infected with flesh warp.
Check: At the end of each extended rest, the target makes a check if it is at stage 1 or 2.
25 or lower: The stage of the disease increases by one.
26-30: No Change
31 or higher: The stage of the disease decreases by one.

Published in Demonomicon, page(s) 146.